Iron(III)/O₂-Mediated Regioselective Oxidative Cleavage of 1-Arylbutadienes to Cinnamaldehydes

Amit Bhowmik and Rodney A. Fernandes*

*Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076, Maharashtra, India, Email: rfernandchem.iitb.ac.in

A. Bhowmik, R. A. Fernandes, Org. Lett., 2019, 21, 9203-9207.

DOI: 10.1021/acs.orglett.9b03562

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Abstract

Iron(III) sulfate mediates a simple and efficient regioselective oxidative cleavage of 1-arylbutadienes in the presence of oxygen. The reaction offers good yields, excellent regioselectivity, and good functional group tolerance.

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Regioselective Disulfide-Catalyzed Photocatalytic Oxidative Cleavage of 1-Arylbutadienes to Cinnamaldehydes

R. A. Fernandes, P. Kumar, A. Bhowmik, D. A. Gorve, Org. Lett., 2022, 24, 3436-3439.

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Key Words

oxidative cleavage, enals, oxygen

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ID: J54-Y2019