Mn-Enabled Radical-Based Alkyl-Alkyl Cross-Coupling Reaction from 4-Alkyl-1,4-dihydropyridines
Jie Wang, Yu-Bo Pang, Na Tao, Run-Sheng Zeng* and Yingsheng Zhao*
*College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, Jiangsu 215123, China,
Email: zengrunsheng
suda.edu.cn, yszhaosuda.edu.cn
J. Wang, Y.-B. Pang, N. Tao, R.-S. Zeng, Y. Zhao, J. Org. Chem., 2019, 84, 15315-15322.
DOI: 10.1021/acs.joc.9b02323
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Abstract
A domino dehydrochlorination/Mn-enabled radical-based alkyl-alkyl cross-coupling reaction allows a highly efficient alkylation of β-chloro ketones via in situ-generated α,β-unsaturated ketones as reaction intermediates.
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Key Words
ID: J42-Y2019
