Cu-Catalyzed Carbonylative Silylation of Alkyl Halides: Efficient Access to Acylsilanes
Li-Jie Cheng and Neal P. Mankad*
*Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607, United States,
Email: npm
uic.edu
L.-J. Cheng, N. P. Mankad, J. Am. Chem. Soc., 2020, 142, 80-84.
DOI: 10.1021/jacs.9b12043
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Abstract
A Cu-catalyzed carbonylative silylation of unactivated alkyl halides enables an efficient synthesis of alkyl-substituted acylsilanes in high yield. A variety of functional groups are tolerated under the mild reaction conditions, and primary, secondary, and tertiary alkyl halides are all applicable.
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Key Words
ID: J48-Y2020
