The Development of Efficient Protocols for the Palladium-Catalyzed Cyclization Reactions of Secondary Amides and Carbamates
Bryant H. Yang and Stephen L. Buchwald
*Department of Chemistry, Massachusetts Institute of Technology, Room 18-490, Cambridge, Massachusetts 02139, Email: sbuchwalmit.edu
B. H. Yang, S. L. Buchwald, Org. Lett., 1999, 1, 35-37.
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With the proper choice of palladium catalyst, ligand, and base, five-, six-, and seven-membered rings are formed efficiently from secondary amide or secondary carbamate precursors.
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indolines, oxindoles, tetrahydroquinolines, dihydroquinolinones, benzo-fused N-heterocycles