General Procedure for the Synthesis of α-Amino Phosphonates from Aldehydes and Ketones Using Indium(III) Chloride as a Catalyst
Brindaban C. Ranu*, Alakananda Hajra and Umasish Jana
*Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata - 700032, India, Email: ocbcriacs.res.in
B. C. Ranu, A. Hajra, U. Jana, Org. Lett., 1999, 1, 1141-1143.
DOI: 10.1021/ol990079g
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Abstract
A simple, efficient, and general one-pot reaction of aldehydes and ketones with amines in the presence of indium(III) chloride as a catalyst provides α-amino phosphonates. Sonication accelerates the reaction.
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Key Words
Kabachnik-Fields Reaction, Sonochemistry, Multicomponent Reactions
ID: J54-Y1999