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Copper-Mediated Cross-Coupling of Aryl Boronic Acids and Alkyl Thiols

Prudencio S. Herradura, Kathleen A. Pendola and R. Kiplin Guy*

*University of California at San Francisco, 513 Parnassus Avenue, San Francisco, California 94143-0446, Email: kip.guyuky.edu

P. S. Herradura, K. A. Pendola, R. K. Guy, Org. Lett., 2000, 2, 2019-2022.

DOI: 10.1021/ol005832g



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Abstract

Copper(II) acetate and pyridine mediate a cross-coupling of aryl boronic acids and alkanethiols in anhydrous dimethylformamide to afford aryl alkyl sulfides in good yield.

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Key Words

Chan-Lam Coupling, Aryl Sulfides


ID: J54-Y2000