A Catalyst for Efficient and Highly Enantioselective Hydrogenation of Aromatic, Heteroaromatic, and α,β-Unsaturated Ketones
Mark J. Burk, William Hems, Daniela Herzberg, Christophe Malan and Antonio Zanotti-Gerosa*
*Chirotech Technology Limited, Ascot Fine Chemicals, Cambridge Science Park, Milton Road, Cambridge CB4 0WG, U.K.,
Email: antonio.zanotti-gerosa
matthey.com
M. J. Burk, W. Hems, D. Herzberg, C. Malan, A. Zanotti-Gerosa, Org. Lett., 2000, 2, 4173-4176.
DOI: 10.1021/ol000309n
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Abstract
PhanePhos-ruthenium-diamine complexes efficiently catalyze an asymmetric hydrogenation of a wide range of aromatic, heteroaromatic, and α,β-unsaturated ketones with excellent enantioselectivity.
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Key Words
reduction of carbonyl compounds, hydrogen
ID: J54-Y2000
