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Strong Bicyclic Guanidine Base-Promoted Wittig and Horner-Wadsworth-Emmons Reactions

Daniele Simoni*, Marcello Rossi, Riccardo Rondanin, Angelica Mazzali, Riccardo Baruchello, Cinzia Malagutti, Marinella Roberti and Francesco Paolo Invidiata

*Dipartimento di Scienze Farmaceutiche, Università di Ferrara, Via Fossato di Mortara 17−19, 44100 Ferrara, Italy, Email: daniele.simoniunife.it

D. Simoni, M. Rossi, R. Rondanin, A. Mazzali, R. Baruchello, C. Malagutti, M. Roberti, F. P. Ividiata, Org. Lett., 2000, 2, 3765-3768.

DOI: 10.1021/ol0001665



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Abstract

The guanidine bases TBD and MTBD promote convenient Wittig and Horner-Wadsworth-Emmons reactions under mild reaction conditions with high efficiency and facile isolation of the final products.

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Key Words

Wittig reaction


ID: J54-Y2000