A New Condensation Reaction for the Synthesis of Carboxylic Esters from Nearly Equimolar Amounts of Carboxylic Acids and Alcohols Using 2-Methyl-6-nitrobenzoic Anhydride
Isamu Shiina, Ryoutarou Ibuka, Mari Kubota
*Department of Applied Chemistry, Faculty of Science, Tokyo University of ScienceKagurazaka, Shinjuku-ku, Tokyo,
Email: shiina
rs.tus.ac.jp
I. Shiina, R. Ibuka, M. Kubota, Chem. Lett., 2002, 286-287.
DOI: 10.1246/cl.2002.286
see article for more reactions
Abstract
The combination of 2-methyl-6-nitrobenzoic anhydride with triethylamine in the presence of a catalytic amount of 4-(dimethylamino)pyridine enables the synthesis of various carboxylic esters in excellent yields with high chemoselectivities from nearly equimolar amounts of carboxylic acids and alcohols.
see article for more examples
Key Words
ID: JXX-Y2002
