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Visible Light-Induced Amide Bond Formation

Wangze Song*, Kun Dong and Ming Li

*State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian 116024, P. R. China, Email:

W. Song, K. Dong, M. Li, Org. Lett., 2020, 22, 371-375.

DOI: 10.1021/acs.orglett.9b03905

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An organic photoredox catalyst promotes a metal-, base-, and additive-free amide bond formation reaction in high yields. This green approach offers a broad substrate scope, good compatibility with water and air, and tolerates functional groups such as alcohols, phenols, ethers, esters, halogens, or heterocycles.

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Key Words

Amides, Photochemistry, Organocatalysis, Green Chemistry

ID: J54-Y2020