Nickel-Catalyzed Asymmetric Hydrocyanation of Allenes

Jinguo Long, Jihui Gao and Xianjie Fang*

*School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, People's Republic of China, Email: fangxjsjtu.edu.cn

J. Long, J. Gao, X. Fang, Org. Lett., 2020, 22, 376-380.

DOI: 10.1021/acs.orglett.9b03938

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Abstract

A (R,R)-Ph-BPE-Ni(0) complex catalyzes an enantioselective hydrocyanation of allenes to provide optically active allylic nitriles in good yield with excellent enantioselectivities.

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Highly Enantioselective Nickel-Catalyzed Hydrocyanation of Disubstituted Methylenecyclopropanes Enabled by TADDOL-based Diphosphite Ligands

R. Yu, X. Fang, Org. Lett., 2020, 22, 493-496.

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Key Words

cyanation

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ID: J54-Y2020