4,5-Dioxo-imidazolinium Cation Activation of 1-Acyl-1-carbamoyl Oximes: Access to Cyanoformamides Using Dichloroimidazolidinedione
Yu Gao, Zhihao Zhang, Zhenjiang Li*, Tianfo Guo, Yuejia Zhu, Zhiwei Yao, Bo Liu, Yongqiang Li and Kai Guo*
*College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, 30 Puzhu Road South, Nanjing 211816, P. R. China, Email: zjlinjtech.edu.cn, guoknjtech.edu.cn
Y. Gao, J. Zhang, Z. Li, T. Guo, Y. Zhu, Z. Yao, B. Liu, Y. Li, L. Guo, J. Org. Chem., 2020, 85, 1087-1096.
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4,5-Dioxo-imidazolinium cation activation of 1-acyl-1-carbamoyl oximes provides cyanoformamides with very good yields in short reaction times. This method of activation offers high reactivity, exhibits a high functional group compatibility with mild conditions, and could be scaled up easily.
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