A Method for the Preparation of β-Amino-α,β-unsaturated Carbonyl Compounds: Study of Solvent Effect and Mechanism
R. S. Reyno, Akash Sugunan, S. Ranganayakulu, Cherumuttathu H. Suresh and Goreti Rajendar*
*School of Chemistry, Indian Institute of Science Education and Research, Thiruvananthapuram, Kerala 695551, India,
Email: rajendar
iisertvm.ac.in
R. S. Reyno, A. Sugunan, S. Ranganayakulu, C. H. Suresh, G. Rajendar, Org. Lett., 2020, 22, 1040-1045.
DOI: 10.1021/acs.orglett.9b04531
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Abstract
Bench-stable sodium 3-oxo-enolates can be reacted with amines in the presence of an acid and a desiccant to provide β-amino-α,β-unsaturated carbonyl compounds.
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Key Words
ID: J54-Y2020
