tert-Butyl Hydroperoxide-Mediated Oxo-Sulfonylation of 2H-Indazoles with Sulfinic Acid toward Indazol-3(2H)-ones
Payel Ghosh, Susmita Mondal and Alakananda Hajra*
*Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India, Email: alakananda.hajravisva-bharati.ac.in
P. Ghosh, S. Mondal, A. Hajra, Org. Lett., 2020, 22, 1086-1090.
DOI: 10.1021/acs.orglett.9b04617 (free Supporting Information)
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An efficient oxo-sulfonylation protocol enables the synthesis of N-sulfonylated indazolones from 2H-indazoles employing sulfinic acid as a sulfonylating agent in the presence of tert-butyl hydroperoxide (TBHP) under ambient air. A series of structurally diverse 1-sulfonylindazol-3(2H)-one derivatives were obtained in good yields.
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