Electrochemical Oxidative Oxydihalogenation of Alkynes for the Synthesis of α,α-Dihaloketones
Xiangtai Meng, Yu Zhang, Jinyue Luo, Fei Wang, Xiaoji Cao and Shenlin Huang*
*Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, P. R. China, Email: shuangnjfu.edu.cn
X. Meng, Y. Zhang, J. Luo, F. Wang, X. Cao, S. Huang, Org. Lett., 2020, 22, 1169-1174.
DOI: 10.1021/acs.orglett.0c00052
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Abstract
An electrochemical oxydihalogenation of alkynes enables the preparation of α,α-dihaloketones using CHCl3, CH2Cl2, ClCH2CH2Cl, and CH2Br2 as the halogen source at room temperature.
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Key Words
oxygenation, chlorination, bromination, electrochemistry
ID: J54-Y2020