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Development of a Continuous Flow Photoisomerization Reaction Converting Isoxazoles into Diverse Oxazole Products

Cormac Bracken and Marcus Baumann*

*School of Chemistry, University College Dublin, Science Centre South, Belfield, Dublin 4, Ireland, Email:

C. Bracken, M. Baumann, J. Org. Chem., 2020, 85, 2607-2617.

DOI: 10.1021/acs.joc.9b03399

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A continuous flow process converts isoxazoles into their oxazole counterparts via a photochemical transposition reaction. A series of di- and trisubstituted oxazoles were realized through this rapid and mild flow process.

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Key Words

oxazoles, flow chemistry, photochemistry

ID: J42-Y2020