Development of a Continuous Flow Photoisomerization Reaction Converting Isoxazoles into Diverse Oxazole Products
Cormac Bracken and Marcus Baumann*
*School of Chemistry, University College Dublin, Science Centre South, Belfield, Dublin 4, Ireland,
Email: marcus.baumann
ucd.ie
C. Bracken, M. Baumann, J. Org. Chem., 2020, 85, 2607-2617.
DOI: 10.1021/acs.joc.9b03399
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Abstract
A continuous flow process converts isoxazoles into their oxazole counterparts via a photochemical transposition reaction. A series of di- and trisubstituted oxazoles were realized through this rapid and mild flow process.
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Key Words
oxazoles, flow chemistry, photochemistry
ID: J42-Y2020
