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Aroylation of Electron-Rich Pyrroles under Minisci Reaction Conditions

Joydev K. Laha*, Mandeep Kaur Hunjan, Shalakha Hegde and Anjali Gupta

*Department of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research, S. A. S. Nagar, Punjab 160062, India, Email: jlahaniper.ac.in

J. K. Laha, M. K. Hunjan, S. Hegde, A. Gupta, Org. Lett., 2020, 22, 1442-1447.

DOI: 10.1021/acs.orglett.0c00041 (free Supporting Information)


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Abstract

A regioselective Minisci monoacylation of electron-rich pyrroles under silver-free neutral conditions provides the desired products without polymerization of pyrroles.

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Key Words

pyrroles, potassium peroxydisulfate


ID: J54-Y2020