An Iodide-Mediated Transition-Metal-Free Strategy towards Unsymmetrical Diaryl Sulfides via Arylhydrazines and Thiols
Farnaz Jafarpour*, Mohammad Asadpour, Meysam Azizzade, Mehran Ghasemi, Saideh Rajai-Daryasarei
*School of Chemistry, College of Science, University of Tehran, P.O. Box 14155-6455, Tehran, Iran, Email: jafarpurkhayam.ut.ac.ir
F. Jafarpour, M. Asadpour, M. Azizzade, M. Ghasemi, S. Rajai-Daryasarei, Synthesis, 2020, 52, 727-734.
A mild, scalable iodine-mediated oxidative cross-coupling reaction of arylhydrazines and thiols enables the construction of thioethers (sulfides) in the absence of any transition metals or photocatalysts. A variety of unsymmetrical diaryl sulfides with broad substrate scope both on thiols and hydrazines were synthesized in high yields in water at room temperature.
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