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A Pd-Catalyzed Site-Controlled Isomerization of Terminal Olefins

Wenlong Ren, Fei Sun, Jianxiao Chu and Yian Shi*

*Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States, Email:

W. Ren, F. Sun, J. Chu, Y. Shi, Org. Lett., 2020, 22, 1868-1873.

DOI: 10.1021/acs.orglett.0c00168

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An effective Pd-catalyzed isomerization of terminal olefins with 2-PyPPh2 as the ligand provides trans-2-olefins bearing various functional groups with high regio- and stereoselectivity under mild reaction conditions. The ligand is crucial for the reaction.

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Key Words


ID: J54-Y2020