A Pd-Catalyzed Site-Controlled Isomerization of Terminal Olefins

Wenlong Ren, Fei Sun, Jianxiao Chu and Yian Shi*

*Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States, Email: Yian.Shicolostate.edu

W. Ren, F. Sun, J. Chu, Y. Shi, Org. Lett., 2020, 22, 1868-1873.

DOI: 10.1021/acs.orglett.0c00168

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Abstract

An effective Pd-catalyzed isomerization of terminal olefins with 2-PyPPh₂ as the ligand provides trans-2-olefins bearing various functional groups with high regio- and stereoselectivity under mild reaction conditions. The ligand is crucial for the reaction.

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Key Words

isomerizations

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ID: J54-Y2020