Electrochemical Synthesis of Carbodiimides via Metal/Oxidant-Free Oxidative Cross-Coupling of Amines and Isocyanides
Bhanwar Kumar Malviya, Pradeep K. Jaiswal, Ved Prakash Verma, Satpal Singh Badsara and Siddharth Sharma*
*Department of Chemistry, Mohanlal Sukhadia University, Udaipur, 313001, India, Email: siddharthmlsu.ac.in
B. K. Malviya, P. K. Jaiswal, V. P. Verma, S. S. Badsara, S. Sharma, Org. Lett., 2020, 22, 2323-2327.
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An electrochemical oxidative cross-coupling of amines with aryl and aliphatic isocyanides proceeds without involving any transition-metal catalyst, oxidant, or toxic reagents in an undivided cell to provide carbodiimides in good yields with H2 as the only byproduct. A subsequent optional hydrolysis provides ureas in situ.
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