N-Nitroheterocycles: Bench-Stable Organic Reagents for Catalytic Ipso-Nitration of Aryl- and Heteroarylboronic Acids
Kun Zhang, Alena Budinská, Alessandro Passera and Dmitry Katayev*
*Department of Chemistry and Biosciences, Swiss Federal Institute of Technology, Vladimir-Prelog-Weg-2, 8093, Zürich, Switzerland, Email: katayevinorg.chem.ethz.ch
K. Zhang, A. Budinská, A. Passera, D. Katayev, Org. Lett., 2020, 22, 2714-2719.
DOI: 10.1021/acs.orglett.0c00671 (free Supporting Information)
see article for more reactions
Photocatalytic and metal-free ipso-nitrations of readily available boronic acid derivatives provide various aromatic and heteroaromatic nitro compounds in very good yields using non-metal-based, bench-stable, and recyclable nitrating reagents. These methods are operationally simple, mild, regioselective, and possess excellent functional group compatibility.
see article for more examples