AgN3-Catalyzed Hydroazidation of Terminal Alkynes and Mechanistic Studies
Shanshan Cao, Qinghe Ji, Huaizhi Li, Maolin Pang*, Haiyan Yuan, Jingping Zhang* and Xihe Bi*
*Chinese Academy of Sciences, Changchun 130022; Northeast Normal University, Changchun 130024, China, Email: mlpangciac.ac.cn, jpzhangnenu.edu.cn, bixh507nenu.edu.cn
S. Cao, Q. Ji, H. Li, M. Pang, H. Yuan, J. Zhang, X. Bi, J. Am. Chem. Soc., 2020, 142, 7083-7091.
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A AgN3-catalyzed hydroazidation of terminal alkynes provides vinyl azides in good yields. AgN3 proved to be a highly robust catalyst, as the loading of AgN3 could be as low as 5 mol %.
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proposed concerted addition
Z. Liu, P. Liao, X. Bi, Org. Lett., 2014, 16, 3668-3671.