Visible-Light-Induced, Base-Promoted Transition-Metal-Free Dehalogenation of Aryl Fluorides, Chlorides, Bromides, and Iodides

Ting-Hui Ding, Jian-Ping Qu* and Yan-Biao Kang*

*Nanjing Tech University, Nanjing 211816; University of Science and Technology of China, Hefei, Anhui 230026, China, Email: ias_jpqunjtech.edu.cn, ybkangustc.edu.cn

T.-H. Ding, J.-P. Qu, Y.-B. Kang, Org. Lett., 2020, 22, 3084-3088.

DOI: 10.1021/acs.orglett.0c00827

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Abstract

A combined visible light and base system initiates a radical-mediated hydrogenation of aryl fluorides, chlorides, bromides, and iodides to the corresponding (hetero)arenes with excellent yields under mild conditions. This simple and efficient transition-metal-free hydrogenation tolerates various functional groups.

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proposed mechanism

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Key Words

dehalogenations, photochemistry

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ID: J54-Y2020