A Hg(OTf)2-Catalyzed Enolate Umpolung Reaction Enables the Synthesis of Coumaran-3-ones and Indolin-3-ones
Zhouting Rong*, Weican Hu, Ning Dai and Guoying Qian*
*College of Biological and Environmental Sciences, Zhejiang Wanli University, Ningbo 315100, People’s Republic of China, Email: zrongzwu.edu.cn, qiangyzwu.edu.cn
Z. Rong, W. Hu, N. Dai, G. Qian, Org. Lett., 2020, 22, 3245-3250.
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A Hg(OTf)2-catalyzed N-oxide addition to alkynes forms an enolonium species, that can undergo intramolecular nucleophilic attack by hydroxyl or amino groups, providing various coumaran-3-ones and indolin-3-ones via an enolate umpolung reactivity.
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