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Visible-Light-Mediated Access to Phosphate Esters

Alya Inial, Fabrice Morlet-Savary, Jacques Lalevée, Annie-Claude Gaumont and Sami Lakhdar*

*Université Paul Sabatier, Laboratoire Hétérochimie Fondamentale et Appliquée (LHFA, UMR 5069), 118 Route de Narbonne, 31062, Toulouse Cedex 09, France, Email:

A. Inial, F. Morlet-Savary, J. Lalevée, A.-C. Gaumont, S. Lakhdar, Org. Lett., 2020, 22, 4404-4407.

DOI: 10.1021/acs.orglett.0c01409

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A simple visible-light photocatalytic reaction of N-alkoxypyridinium salts with phosphites provides a broad range of phosphate esters under mild conditions. The protocol was successfully applied to the synthesis of biologically relevant structures.

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Key Words

phosphates, photochemistry

ID: J54-Y2020