Dehydrative Allylation of α C(sp³)-H Bonds of Alkylamines with Allylic Alcohols

Yusuke Masuda, Misato Ito and Masahiro Murakami*

*Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto 615-8510, Japan, Email: murakamisbchem.kyoto-u.ac.jp

Y. Masuda, M. Ito, M. Murakami, Org. Lett., 2020, 22, 4467-4470.

DOI: 10.1021/acs.orglett.0c01464

---

see article for more reactions

Abstract

A combination of a photoredox and a palladium catalyst catalyzes a dehydrative coupling reaction of alkyl amines with allylic alcohols to provide a range of homoallylic amines.

see article for more examples

---

---

Key Words

homoallylic amines, pyrrolidines, photochemistry

---

ID: J54-Y2020