Utility of Organoboron Reagents in Arylation of Cyclopropanols via Chelated Pd(II) Catalysis: Chemoselective Access to β-Aryl Ketones

Thangeswaran Ramar, Murugaiah A. M. Subbaiah* and Andivelu Ilangovan*

*Department of Chemistry, Bharathidasan University, Palkalaiperur, Thiruchirapalli 620024, India, Email: murugaiah.andappansyngeneintl.com, ilangovanbdu.ac.in

T. Ramar, M. A. M. Subbaiah, A. Ilangovan, J. Org. Chem., 2020, 85, 7711-7727.

DOI: 10.1021/acs.joc.0c00160

---

see article for more reactions

Abstract

A chelated Pd(II) complex catalyzes a coupling of organoborane reagents with cyclopropanol-derived β-ketone enolates to provide synthetically important β-aryl ketone intermediates in a chemoselective fashion.

see article for more examples

---

---

Orchestrating a β-Hydride Elimination Pathway in Palladium(II)-Catalyzed Arylation/Alkenylation of Cyclopropanols Using Organoboron Reagents

T. Ramar, M. A. M. Subbaiah, A. Ilangovan, J. Org. Chem., 2022, 87, 4508-4523.

---

Key Words

β-aryl ketones, copper compounds

---

ID: J42-Y2020