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Utility of Organoboron Reagents in Arylation of Cyclopropanols via Chelated Pd(II) Catalysis: Chemoselective Access to β-Aryl Ketones

Thangeswaran Ramar, Murugaiah A. M. Subbaiah* and Andivelu Ilangovan*

*Department of Chemistry, Bharathidasan University, Palkalaiperur, Thiruchirapalli 620024, India, Email: murugaiah.andappansyngeneintl.com, ilangovanbdu.ac.in

T. Ramar, M. A. M. Subbaiah, A. Ilangovan, J. Org. Chem., 2020, 85, 7711-7727.

DOI: 10.1021/acs.joc.0c00160 (free Supporting Information)


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Abstract

A chelated Pd(II) complex catalyzes a coupling of organoborane reagents with cyclopropanol-derived β-ketone enolates to provide synthetically important β-aryl ketone intermediates in a chemoselective fashion.

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Key Words

β-aryl ketones, copper compounds


ID: J42-Y2020