Ruthenium(II)-Complex-Catalyzed Acceptorless Double Dehydrogenation of Primary Amines to Nitriles
Muthukumar Kannan, Senthilkumar Muthaiah*
*Department of Chemistry, National Institute of Technology Kurukshetra, Kurukshetra-136119, Haryana, India, Email: msenthilnitkkr.ac.in
M. Kannan, S. Muthaiah, Synlett, 2020, 31, 1073-1076.
An in situ formed complex of commercially available dichloro(1,5-cyclooctadiene) ruthenium(II) and simple hexamethylenetetramine catalyzes acceptorless dehydrogenative oxidation of primary amines into nitriles in good yields. The synthetic protocol is highly selective and produces hydrogen as the sole byproduct.
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ruthenium, amines, nitriles, dehydrogenation