Nickel-Catalysed Allylboration of Aldehydes
Francesca M. Dennis, Craig C. Robertson, Benjamin M. Partridge*
*Department of Chemistry, University of Sheffield, Dainton Building, Sheffield, S3 7HF, UK,
Email: b.m.partridge
sheffield.ac.uk
F. M. Dennis, C. C. Robertson, B. M. Partridge, Synthesis, 2020, 52, 1903-1914.
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Abstract
A nickel complex catalyzes an allylboration of aldehydes, facilitating the preparation of homoallylic alcohols in high diastereoselectivity. Allylation occurs through a well-defined six-membered transition state, with nickel acting as a Lewis acid.
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Key Words
allylboration, boronic esters, catalysis, homoallylic alcohols, nickel
ID: J66-Y2020
