Ir-Catalyzed Reversible Acceptorless Dehydrogenation/Hydrogenation of N-Substituted and Unsubstituted Heterocycles Enabled by a Polymer-Cross-Linking Bisphosphine
Deliang Zhang, Tomohiro Iwai* and Masaya Sawamura*
*Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan, Email: iwai-tsci.hokudai.ac.jp, sawamurasci.hokudai.ac.jp
D. Zhang, T. Iwai, M. Sawamura, Org. Lett., 2020, 22, 5240-5245.
DOI: 10.1021/acs.orglett.0c01874 (free Supporting Information)
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The polystyrene-cross-linking bisphosphine ligand PS-DPPBz was effective for the Ir-catalyzed reversible acceptorless dehydrogenation/hydrogenation of N-heterocycles. Notably, this protocol is applicable to the dehydrogenation of a broad range of indoline derivatives.
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