Catalytic Dealkylative Synthesis of Cyclic Carbamates and Ureas via Hydrogen Atom Transfer and Radical-Polar Crossover
Takuya Nagai, Nao Mimata, Yoshihiro Terada, Chikayoshi Sebe and Hiroki Shigehisa*
*Faculty of Pharmacy, Musashino University 1-1-20 Shinmachi, Nishitokyo-shi, Tokyo 202-8585, Japan,
Email: cgehisa
musashino-u.ac.jp
T. Nagai, N. Mimata, Y. Terada, C. Sebe, H. Shigehisa, Org. Lett., 2020, 22, 5522-5527.
DOI: 10.1021/acs.orglett.0c01872
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Abstract
A functional-group-tolerant and scalable cobalt-catalyzed cyclization of alkenyl carbamates and alkenyl isoureas provides common five- and six-to-eight-membered cyclic carbamates and ureas via transition-metal hydrogen atom transfer and radical-polar crossover.
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Key Words
oxazolidinones, imidazolidinones
ID: J54-Y2020
