Copper-Catalyzed Methylthiolation of Aryl Iodides and Bromides with Dimethyl Disulfide in Water
Ying-yu Wang, Xiang-mei Wu*, Ming-hua Yang
*Department of Chemistry, Lishui University, Lishui, Zhejiang
323000, P. R. of China, Email: mhyang
lsu.edu.cn
Y.-y. Wang, X.-m. Wu, M.-h. Yang, Synlett, 2020, 31, 1226-1230.
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Abstract
A copper-catalyzed coupling of aryl iodides with dimethyl disulfide in water enables an efficient route to aryl methyl sulfides in good yields. The reaction tolerates electron-donating and electron-withdrawing functional groups.
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Key Words
methylthiolation, aryl halides, dimethyl disulfide, aryl methyl sulfides, copper catalysis
ID: J72-Y2020
