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Photoredox Generation of Sulfonyl Radicals and Coupling with Electron Deficient Olefins

Yiding Chen, Nicole McNamara, Oliver May, Thanigaimalai Pillaiyar, David C. Blakemore and Steven V. Ley*

*Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K., Email:

Y. Chen, N. McNamara, O. May, T. Pillaiyar, D. C. Blakemore, S. V. Ley, Org. Lett., 2020, 22, 5746-5748.

DOI: 10.1021/acs.orglett.0c01730


Various sulfone tetrazoles were activated via iridium photoredox catalysis in the presence of DMAP to give dialkyl sulfones. The presumed sulfone radical intermediates were trapped by a range of electron-deficient olefins in generally good to excellent yields.

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Key Words

sulfones, photochemistry

ID: J54-Y2020