Iodine-Mediated Electrochemical C(sp²)-H Amination: Switchable Synthesis of Indolines and Indoles

Kangfei Hu, Yan Zhang, Zhenghong Zhou, Yu Yang, Zhenggen Zha* and Zhiyong Wang*

*University of Science and Technology of China, Hefei, Anhui 230026, People’s Republic of China, Email: zgzhaustc.edu.cn, zwang3ustc.edu.cn

K. Hu, Y. Zhang, Z. Zhou, Y. Yang, Z. Zha, Z. Wang, Org. Lett., 2020, 22, 5773-5777.

DOI: 10.1021/acs.orglett.0c01821

---

see article for more reactions

Abstract

A metal-free electrochemical intramolecular C(sp²)-H amination using iodine as a mediator enables a switchable synthesis of indoline and indole derivatives from easily available 2-vinyl anilines.

see article for more examples

---

---

Key Words

indolines, indoles, electrochemistry

---

ID: J54-Y2020