Co(III)-Catalyzed Annulative Vinylene Transfer via C-H Activation: Three-Step Total Synthesis of 8-Oxopseudopalmatine and Oxopalmatine
Xinghua Li, Ting Huang, Ying Song, Yue Qi, Limin Li, Yanping Li, Qi Xiao* and Yuanfei Zhang*
*Guangxi Key Laboratory of Natural Polymer Chemistry and Physics, Nanning Normal University, Nanning 530001, China,
Email: yfzhang
gxtc.edu.cn, qi.xiaonnnu.edu.cn
X. Li, T. Huang, Y. Song, Y. Qi, L. Li, Y. Li, Q. Xiao, Y. Zhang, Org. Lett., 2020, 22, 5925-5930.
DOI: 10.1021/acs.orglett.0c02016
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Abstract
A Co(III)-catalyzed redox-neutral annulation of benzamides and acrylamides with vinylene carbonate provides isoquinolinones and pyridinones in very good yields. This protocol tolerates diverse functional groups and substitution patterns.
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Key Words
ID: J54-Y2020
