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Transition-Metal-Free Borylation of Aryl Bromide Using a Simple Diboron Source

Taeho Lim, Jeong Yup Ryoo and Min Su Han*

*Department of Chemistry, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Republic of Korea, Email:

T. Lim, J. Y. Ryoo, M. S. Han, J. Org. Chem., 2020, 85, 10966-10972.

DOI: 10.1021/acs.joc.0c01065 (free Supporting Information)


A simple transition-metal-free borylation reaction of aryl bromides with bis-boronic acid (BBA) provides arylboronic acids at mild temperatures directly without any deprotection steps and purified by conversion to trifluoroborate salts. The functional group tolerance was considerably high.

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Key Words

aryltrifluoroborate salts

ID: J42-Y2020