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Nickel-Catalyzed Thiocarbonylation of Arylboronic Acids with Sulfonyl Chlorides for the Synthesis of Thioesters

Xinxin Qi, Zhi-Peng Bao, Xin-Tong Yao and Xiao-Feng Wu*

*Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Straße 29a, Rostock 18059, Germany, Email:

X. Qi, Z.-P. Bao, X.-T. Yao, X.-F. Wu, Org. Lett., 2020, 22, 6671-6676.

DOI: 10.1021/acs.orglett.0c02541


A nickel-catalyzed thiocarbonylation of arylboronic acid with sulfonyl chlorides in the presence of Mo(CO)6 as CO source and reductant provides a broad range of thioesters in good yields with good functional group tolerance.

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Key Words

Carboxylations, Thioesters, Multicomponent Reactions

ID: J54-Y2020