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Radical-Dual-Difunctionalization and Trifluoromethylative Decarboxylation of Two Different Alkenes

Jing Zhao, Ren-Xiang Liu, Cui-Ping Luo and Luo Yang*

*Key Laboratory for Green Organic Synthesis and Application of Hunan Province, College of Chemistry, Xiangtan University, Hunan 411105, P.R. China, Email:

J. Zhao, R.-X. Liu, C.-P. Luo, L. Yang, Org. Lett., 2020, 22, 6776-6779.

DOI: 10.1021/acs.orglett.0c02267

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A convenient Fe-catalyzed A-D-A-T-type radical-dual-difunctionalization and cross-coupling of two different alkenes provides chain elongated and trifluoromethylated aromatic alkenes.

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proposed mechanism

Key Words

trifluoromethylation, alkenylation, multicomponent reactions, DTBP

ID: J54-Y2020