Organic Chemistry Portal

Abstracts

Search:

Sulfuryl Fluoride Promoted Thiocyanation of Alcohols: A Practical Method for Preparing Thiocyanates

Guofu Zhang, Lidi Xuan, Yiyong Zhao, Chengrong Ding*

*College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, P. R. of China, Email: dingcrzjut.edu.cn

G. Zhang, L. Xuan, Y. Zhao, C. Ding, Synlett, 2020, 31, 1413-1417.

DOI: 10.1055/s-0040-1707151



see article for more reactions

Abstract

SO2F2 promotes a one-step synthesis of thiocyanates through C-O bond cleavage of readily available alcohols with ammonium thiocyanate as the thiocyanating agent. A borad range of alcohols reacted with high efficiency in ethyl acetate under mild conditions to afford the corresponding thiocyanates in very good yields with broad functional group compatibility.

see article for more examples



Key Words

sulfuryl fluoride catalysis, alcohols, thiocyanation, ammonium thiocyanate, thiocyanates


ID: J72-Y2020