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"Bulky-Yet-Flexible" α-Diimine Palladium-Catalyzed Reductive Heck Cross-Coupling: Highly Anti-Markovnikov-Selective Hydroarylation of Alkene in Air

Xu-Wen Yang, Dong-Hui Li, A-Xiang Song and Feng-Shou Liu*

*School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan, Guangdong 528458, China, Email:

X.-W. Yang, D.-H. Li, A.-X. Song, F.-S. Liu, J. Org. Chem., 2020, 85, 11750-11765.

DOI: 10.1021/acs.joc.0c01509

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"Bulky-yet-flexible" palladium complexes catalyze highly anti-Markovnikov-selective hydroarylation of alkenes with (hetero)aryl bromides under aerobic conditions.

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proposed mechanism

Key Words

Heck reaction, arylation

ID: J42-Y2020