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Ozonolysis of Alkynes - A Flexible Route to Alpha-Diketones: Synthesis of AI-2

Joshua L. Alterman, Dua X. Vang, Marissa Roghair Stroud, Larry J. Halverson and George A. Kraus*

*Department of Chemistry, Ames Laboratory, Iowa State University, Ames, Iowa 50011, United States, Email: gakrausiastate.edu

J. L. Alterman, D. X. Vang, M. R. Stroud, L. J. Halverson, G. A. Kraus, Org. Lett., 2020, 22, 7424-7426.

DOI: 10.1021/acs.orglett.0c02182 (free Supporting Information)


Abstract

A low-temperature ozonolysis of alkynes enables a mild synthesis of α-diketones.

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Key Words

ozonolysis, ozone, 1,2-diketones


ID: J54-Y2020