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Photocatalytic Hydromethylation and Hydroalkylation of Olefins Enabled by Titanium Dioxide Mediated Decarboxylation

Qilei Zhu and Daniel G. Nocera*

*Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138-2902, United States, Email: dnocerafas.harvard.edu

Q. Zhu, D. G. Nocera, J. Am. Chem. Soc., 2020, 142, 17913-17918.

DOI: 10.1021/jacs.0c08688 (free Supporting Information)


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Abstract

Anatase titanium dioxide (TiO2) mediates a versatile method for the hydromethylation and hydroalkylation of alkenes at room temperature. The photoexcitation of TiO2 with 390 nm light in the presence of acetic acid and other carboxylic acids generates methyl and alkyl radicals, respectively.

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Key Words

esters, photochemistry


ID: J48-Y2020