Controllable Phosphorylation of Thioesters: Selective Synthesis of Aryl and Benzyl Phosphoryl Compounds
Kaiqiang Xu, Long Liu, Zhaohui Li, Tianzeng Huang, Kang Xiang and Tieqiao Chen*
*Hainan Provincial Key Lab of Fine Chemistry, Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China, Email: chentieqiaohnu.edu.cn
K. Xu, L. Liu, Z. Li, T. Huang, K. Xiang, T. Chen, J. Org. Chem., 2020, 85, 14653-14663.
DOI: 10.1021/acs.joc.0c01557 (free Supporting Information)
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Pd-catalyzed phosphorylations of thioesters provide aryl or alkenyl phosphoryl compounds through decarbonylative coupling, whereas benzyl phosphoryl compounds were produced through deoxygenative coupling when the reactions were carried out in the presence of only a base.
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