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Palladium-Catalyzed Monoarylation of Arylhydrazines with Aryl Tosylates

Yange Huang, Pui Ying Choy, Junya Wang, Man-Kin Tse, Raymond Wai-Yin Sun, Albert Sun-Chi Chan and Fuk Yee Kwong*

*State Key Laboratory of Synthetic Chemistry and Department of Chemistry, The Chinese University of Hong Kong, New Territories, Shatin, Hong Kong, China, Email: fykwongcuhk.edu.hk

Y. Huang, P. Y. Choy, J. Wang, M.-K. Tse, R. W.-Y. Sun, A. S.-C. Chan, F. Y. Kwong, J. Org. Chem., 2020, 85, 14664-14673.

DOI: 10.1021/acs.joc.0c01599


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Abstract

A palladium-catalyzed C-N bond coupling reaction between arylhydrazines and aryl tosylates provides unsymmetrical N,N-diarylhydrazines in very good yields with good functional group compatibility.

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Key Words

hydrazines


ID: J42-Y2020