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Visible-Light Photoredox-Catalyzed Formal [5 + 1] Cycloaddition of N-Tosyl Vinylaziridines with Difluoroalkyl Halides

Yantao Liu, Wen Luo*, Zhenjie Wang, Yuxin Zhao, Jingjing Zhao*, Xuejun Xu, Chaojie Wang and Pan Li*

*College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, People's Republic of China, Email: luowen83163.com, zhaojingjinghenu.edu.cn, panlihenu.edu.cn

Y. Liu, W. Luo, Z. Wang, Y. Zhao, J. Zhao, X. Xu, C. Wang, P. Li, Org. Lett., 2020, 22, 9638-9643.

DOI: 10.1021/acs.orglett.0c03718


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Abstract

An efficient and practical visible-light photoredox-catalyzed formal [5 + 1] cycloaddition of N-tosyl vinylaziridines with difluoroalkyl halides as unique C1 synthons provides pyridines in good yields.

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proposed reaction mechanism



Key Words

pyridines, photochemistry


ID: J54-Y2020