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Highly Efficient and Catalytic Conversion of Aldoximes to Nitriles

Soon Ha Yang and Sukbok Chang

*Department of Chemistry, Ewha Womans University, Seoul 120-750, Korea, Email:

S. H. Yang, S. Chang, Org. Lett., 2001, 3, 4209-4211.

DOI: 10.1021/ol0168768


[RuCl2(p-cymene)]2 catalyzes a highly efficient dehydration of aldoximes in the presence of molecular sieves under essentially neutral and mild conditions to provide various types of cyano compounds in very good yields.

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ID: J54-Y2001