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Rhodium(III)-Catalyzed Direct C-H Arylation of Various Acyclic Enamides with Arylsilanes

Xiaolan Li, Kai Sun, Wenjuan Shen, Yong Zhang, Ming-Zhu Lu, Xuzhong Luo and Haiqing Luo*

*Department of Chemistry & Chemical Engineering, Gannan Normal University, Ganzhou 341000, China, Email:

X. Jiang, G. Wang, Z. Zheng, X. Yu, Y. Hong, H. Xia, C. Yu, Org. Lett., 2021, 23, 31-36.

DOI: 10.1021/acs.orglett.0c03578 (free Supporting Information)

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A Rh(III)-catalyzed β-C(sp2)-H arylation of various acyclic enamides with environmentally friendly arylsilanes offers extraordinary efficacy and stereoselectivity, a wide scope of substrates, and good functional group tolerance.

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proposed mechanism

Key Words

enamides, copper compounds

ID: J54-Y2021