Organic Chemistry Portal



Nickel-Catalyzed Amination of Aryl Chlorides with Amides

Jinpeng Li, Changyu Huang, Daheng Wen, Qingshu Zheng, Bo Tu* and Tao Tu*

*Department of Chemistry, Fudan University, 2005 Songhu Road, Shanghai 200438, China, Email:,

J. Li, C. Huang, D. Wen, Q. Zheng, B. Tu, T. Tu, Org. Lett., 2021, 23, 687-691.

DOI: 10.1021/acs.orglett.0c03836

see article for more reactions


A nickel-catalyzed amination of aryl chlorides with diverse amides via C-N bond cleavage provides a broad range of aromatic amines under mild conditions with excellent functional group tolerance at a low catalyst loading.

see article for more examples

Key Words

aromatic amines

ID: J54-Y2021