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Palladium-Catalyzed Denitrative α-Arylation of Ketones with Nitroarenes

Zhirong Li, Yonggang Peng and Tao Wu*

*The College of Chemistry, Nanchang University, Nanchang, Jiangxi 330031, P. R. China, Email: taowuncu.edu.cn

Z. Li, Y. Peng, T. Wu, A. Das, Org. Lett., 2021, 23, 881-885.

DOI: 10.1021/acs.orglett.0c04104



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Abstract

A palladium-catalyzed α-arylation of ketones with readily available nitroarenes and nitroheteroarenes provides α-aryl and α-heteroaryl ketones. The use of BrettPhos as ligand was crucial for high efficiency.

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Key Words

arylation


ID: J54-Y2021