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Synthesis of Vinylic Sulfones in Aqueous Media

Jeffrey Goh, Manikantha Maraswami and Teck-Peng Loh*

*Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Email:

J. Goh, M. Maraswami, T.-P. Loh, Org. Lett., 2021, 23, 1060-1065.

DOI: 10.1021/acs.orglett.0c04257 (free Supporting Information)


A sulfination of allenic carbonyl compounds provides a wide variety of vinylic sulfones in good yields in aqueous media under very mild conditions. This atom economic reaction offers wide functional group tolerance and a simple isolation by filtration for some products.

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Key Words

Vinylic Sulfones, Green Chemistry

ID: J54-Y2021